Driving the Robustness of Preclinical Research within the Pharmaceutical Industry

Katrina Gore, Director, Pfizer Research Statistics & Joint winner of the 2015 RSS / PSI prize for statistical excellence in the pharmaceutical industry. It is unusual to pick up a recent issue of Nature or Science that doesn’t include an article on the issue of non-reproducible research. It would seem that research is plagued by findings that are not reliable and cannot be reproduced. The pharmaceutical industry is not immune to these same issues. Replication of published research findings is a key component of drug target identification and provides confidence to progress internal drug projects. Additionally, we use data from internal assays to assess the biological and pharmacokinetic activity, selectivity and safety of novel compounds, and to make decisions that impact their progression towards clinical development.

Spotlight

The South Bend Clinic

Even in 1916 the Mayo Clinic was an impressive health care facility. That’s what Dr. Walter Baker, a South Bend surgeon, thought when he visited the nationally known Clinic. It was the first nonprofit group practice in the world, and doctors from a variety of medical specialties came together there to care for patients. They believed “the needs of the patient come first.” So did Dr. Baker. In fact, he was so inspired by what he saw that when he returned to South Bend, he gathered six other specialists, and they formed the South Bend Clinic...

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Spotlight

The South Bend Clinic

Even in 1916 the Mayo Clinic was an impressive health care facility. That’s what Dr. Walter Baker, a South Bend surgeon, thought when he visited the nationally known Clinic. It was the first nonprofit group practice in the world, and doctors from a variety of medical specialties came together there to care for patients. They believed “the needs of the patient come first.” So did Dr. Baker. In fact, he was so inspired by what he saw that when he returned to South Bend, he gathered six other specialists, and they formed the South Bend Clinic...

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