Medical manufactures, can access a specially tailored digital infrastructure from Siemens for the MD&D industry called “Operational Excellence through Smart Manufacturing”. This means to develop a digital infrastructure by using production digital twins to design and simulate manufacturing scenarios, schedule and execute production, enforcing routes, quality inspections to deliver high quality devices. This is also an approach for the small- to medium-sized businesses (SMB), the new emerging market leaders, aiming at creating the same digital infrastructure of their larger competitors to get their own innovation to market, rapidly, cost-efficiently and in compliance with high quality standards international regulatory authorities require.