Optums John Muir Health deal provides a new model for health system collaboration

Medcitynews | July 18, 2019

UnitedHealth Groups Optum division has become a major provider in its own right, vacuuming up independent practices and physician groups nationwide. The companys recently closed acquisition of DaVita Medical Group makes the company one of the top employers of clinicians in the country. Much of the growth has been in its OptumCare subsidy, which is mainly focused on outpatient care settings. A new partnership with Walnut Creek, California-based health system John Muir Health could provide a model of how the company is looking to support the inpatient hospital setting with backend services. As part of the deal, Optum will take over non-clinical functions for the provider ranging from IT services, revenue cycle management, analytics and claims processing. The idea is to allow John Muir to focus on patient care and lower administrative burden, while utilizing Optum data resources to shift its business to value-based care models. “This first-of-its-kind, comprehensive relationship brings the exceptional skills and knowledge of the John Muir Health team together with Optum’s advanced technologies, analytic tools and operational expertise to deliver better health outcomes and patient experiences while reducing the total cost of care,” OptumInsight CEO Eric Murphy said in a statement.

Spotlight

The pandemic hit the healthcare industry hard, but it also weakened the cybersecurity defenses of most providers, making them far more vulnerable to threats such as ransomware. This report, covered across national news, is considered the most significant actionable cybersecurity research over the past several years because it also documents the severe impact on patient care. This executive summary includes critical areas that providers can address starting today.


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HEALTH TECHNOLOGY

Office Ally Announces Acquisition of Bluemark

Office Ally | May 11, 2022

Office Ally, a leading provider of electronic clearinghouse and healthcare software solutions,announced that is has acquired Bluemark, LLC, a provider of specialized healthcare software for healthcare professionals and community-based organizations. Financial terms of the transaction were not disclosed. Founded in 2001, Bluemark provides specialized healthcare software and adaptive technology, including revenue integrity and Medicaid enrollment solutions, for hospitals, health systems, nursing homes and community-based organizations across the country. Bluemark offers four unique products that span Payer Audit Management and Assistance Program Enrollment, enabling healthcare professionals to both enhance reimbursement processes and achieve workflow efficiencies. “As a leader in healthcare revenue cycle software, Bluemark has built an impressive suite of high-quality RCM products that are designed to provide mature cloud-based technology solutions that simplify some of the most complex processes in healthcare finance. Not only are Bluemark’s self-pay and health information handling solutions highly complementary to our solution set at Office Ally, but the company’s network of hospital and health system relationships expands our customer base into some of the largest providers of care in the US.” Chris Hart, CEO of Office Ally “We are thrilled to be growing the Office Ally platform with the addition of Bluemark. Together, we believe there is an incredible opportunity to leverage our extensive network of providers and combined solution set to further scale our offerings as a leading healthcare technology company,” continued Hart. With the acquisition of Bluemark, Office Ally will be able to expand its product set and add new health information handler credentials. In addition, the complementary nature of the two businesses will allow Office Ally to better serve existing customers with an integrated suite of healthcare software solutions now spanning self-pay management and Medicaid enrollment. “Over the last two decades, Bluemark has been a pioneer and innovator in healthcare finance by developing unique solutions to drive the enrollment of self-pay patients into Medicaid and associated benefit programs, as well as the electronic exchange of health information between providers and audit contractors. We are thrilled to be joining Office Ally, and look forward to better serving our customers as the healthcare market continues to evolve,” said Ken Sacks, CEO of Bluemark. About Office Ally Office Ally is a healthcare technology company that offers cloud-based solutions to healthcare providers, independent physician associations (IPAs) and health plans. Office Ally’s platform supports both the management of care and facilitates payments between providers, health plans and patients. Office Ally’s platform is paired with a clearinghouse that enables the secure exchange of healthcare information including claims, remits, and eligibility information between covered entities and across the healthcare market. About Bluemark Bluemark, LLC, is a specialized software and technology developer that provides expert solutions for healthcare professionals. Bluemark helps clients maximize reimbursement and achieve workflow efficiencies through the development of technology-based business process solutions for revenue cycle and HIM audit and compliance processes. Backed by a national footprint and strong industry relationships, Bluemark offers mature SAAS-based technology solutions that are time-tested, proven and positioned to evolve with the healthcare market’s changing needs.

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HEALTH TECHNOLOGY

Titan Medical Announces Purchase Order from Medtronic

Titan Medical Inc. | May 04, 2022

Titan Medical Inc. a medical device company focused on the development and commercialization of innovative surgical technologies for single access robotic-assisted surgery announced receipt of a $2.6 million purchase order from Medtronic plc a global leader in healthcare technology. The order covers the purchase of instruments and cameras that will be used in preclinical activities and the evaluation of Titan Medical as a potential manufacturing and supply partner for Medtronic. “Medtronic has been a great partner for Titan since 2020 and we’re excited about this opportunity to further our work together. Our manufacturing team and capabilities continue to expand at our operations in Chapel Hill. With this order, we will produce instruments and cameras for Medtronic’s evaluation and testing in addition to producing instruments and cameras for our own single-access RAS platform, Enos.” Paul Cataford, Interim President and CEO of Titan For clarity, these agreements are between Medtronic and Titan Medical Inc. Titan Medical is not affiliated with Titan Spine, which Medtronic acquired in 2019. About Titan Medical Titan Medical Inc. a medical device company headquartered in Toronto, Ontario, with operations in Chapel Hill, North Carolina, is focused on enhancing robotic-assisted surgery (RAS) using innovative technology through a single access point. The Enos™ robotic single access surgical system is being developed with an ergonomic focus to provide a surgical experience that imitates real-life movements that surgeons demand. The Enos system includes multi-articulating instruments designed to allow surgeons an increased range of motion in a confined space, with dexterity and the ability to exert the forces necessary to complete common surgical tasks. Titan intends to initially pursue gynecologic surgical indications with the Enos

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FUTURE OF HEALTHCARE

Prenosis Announces Investment from PACE Healthcare Capital, bringing Total Funding to Over $20 million

Prenosis | March 10, 2022

Prenosis, Inc., a precision medicine company,announced a venture investment from PACE Healthcare Capital, an early-stage investment firm committed to improving health outcomes. This investment brings total funding in the company to over$20 million, including partnerships with Foxconn, Roche Diagnostics, the Defense Threat Reduction Agency, and others. Prenosisis leveraging machine learning algorithms trained on deep biological data and broad clinical data to create precise and comprehensive maps of acute disease. Using these maps, Prenosis develops and markets valuable navigational tools to improve patient care by illuminating the optimal treatment pathways for each patient. "This capital will further accelerate our deep biological mapping of acute disease and to further grow the NOSIS™dataset/biobank, which is the largest such dataset/biobank ever created for sepsis," saidBobby Reddy, Jr., CEO and Co-Founder, Prenosis Inc. "Using our mapping technology, we are developing sophisticated methods to define, divide, and conquer diseases. The navigational guidance solutions based on our health state maps will address the critical challenge of sepsis by providing critical and actionable information tailored to each patient's health state." Prenosis is pioneering a revolution in managing acute diseases that have previously eluded conventional methods, starting with sepsis. Sepsis occurs when the immune system reacts abnormally to an infection, setting off a chain of events that leads to tissue damage and organ failure. Sepsis is currently one of the leading causes of mortality in U.S. hospitals, and the WHO estimates that it causes 1 in 5 deaths worldwide1. Prenosis has spent nearly a decade building fit-for-purpose biological and clinical datasets at an unprecedented level to better understand sepsis and other acute care conditions. Using this information, Prenosis has developed patient maps and valuable navigational tools to empower physicians to administer optimal treatment to patients faster. Prenosis' first such tool, the Sepsis ImmunoScoreTM, is a Software-as-a-Medical Device (SaMD) digital diagnostic designed to aid in the risk assessment for progression to sepsis of patients admitted in the emergency department or hospital. Prenosis is currently seeking to obtain FDA clearance for the tool by the end of 2022. The test runs on Prenosis's Immunix™software platform, which interfaces with hospital Electronic Medical Records that hosts multiple products to improve patient care. "Personalized medicine is the next frontier of healthcare. Complex acute diseases, such as sepsis, can only be conquered through a robust understanding of the biological response of each patient's immune system – one patient at a time. Prenosis brings our understanding of the disease patterns to a whole new level and enables physicians to make better decisions faster for their patients. We are excited to partner with Bobby and the whole Prenosis team as they continue to develop their technology and transform the way we understand and provide care for patients with complex acute diseases." Julia Monfrini Peev, Founder and Managing Partner of PACE Healthcare Capital The funding builds on a recent string of strategic partnerships and accolades for Prenosis, including being selected as part of the MedTech Innovator 2021 Showcase, being named the #2 Medtech Startup of 2021 by MDDI, and being asked to present its research at scientific meetings, including the forthcoming 2022 annual meetings for the Society of Critical Care Medicine and the American Thoracic Society. "In addition to support from other investors and partners, PACE Healthcare Capital's involvement is a strong endorsement of our solutions and will help to accelerate our growth as we further expand our proprietary dataset and work towards commercialization of the Immunix™platform later this year," said Reddy. "As we use our technology to map acute disease, we hope to usher in a new age of data-driven treatment and medical discovery." About Prenosis Prenosis is a health tech innovator devoted to ushering in a new era of precision diagnostics in acute care using artificial intelligence. Its Immunix™precision diagnostics platform leverages machine learning algorithms trained on deep biological data and broad clinical data designed to capture and illuminate the complex health states of patients more holistically. Its proprietary NOSISTMdataset is one of the largest and fastest-growing hybrid biomarker-clinical datasets for sepsis care. The Sepsis ImmunoScore™diagnostic on the Immunix™platform has the potential to save thousands of lives and billions of dollars in healthcare spending annually. The Sepsis ImmunoScore™is not yet approved for commercial use in the United States. About PACE Healthcare Capital PACE Healthcare Capitalis an early-stage venture capital firm focused on investing in companies that have developed high-impact solutions to critical healthcare challenges. With decades of combined experience and $1B+ of capital raised and deployed in healthcare, PACE applies institutional-grade investment processes to identify the best entrepreneurs and deploy financial and human capital to help them grow their business.

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MEDICAL DEVICES

CeloNova Announces New Strategic Direction Focused on Creating Partnership

CeloNova BioSciences, Inc. | April 08, 2022

CeloNova BioSciences, Inc. developer and manufacturer of a portfolio of novel surfaced coated technologies, including the proprietary Polyzene™-F nanocoating, announced the strategic decision to focus its core business on creating partnership and co-development opportunities with medical device manufacturers seeking to optimize implant interaction within the body. The company's nanocoated innovation is the result of years of rigorous scientific research and engineering and has been extensively published in numerous academic articles to date. "We are pleased to offer leading medical device manufacturers access to the unique clinical advantages of our Polyzene-F nanocoated technology that has clinically demonstrated low thrombosis, restenosis and inflammation with rapid healing effects," stated Carl St. Bernard, President and Chief Executive Officer of CeloNova. "This technology offers a significant benefit to companies seeking to improve the clinical performance of their implant technologies." "I fully support CeloNova's new strategic direction which allows medical device manufacturers to benefit from long-term biocompatibility and thromboresistance of Polyzene-F. When my students and I set out to study the hemocompatibility of this inorganic polymer in our lab in Heidelberg Germany, we soon realized its potential to significantly limit a wide range of implant complications and being broadly applied in the human body and in biomedical devices." Professor Dr. Michael Grunze, Former Chair and Professor (emeritus) at the Institute of Applied Physical Chemistry of the Ruprecht-Karls-University in Heidelberg and co-inventor of Polyzene-F CeloNova is based on a rich history of medical innovation with two PzF coated medical implants successfully commercialized in the U.S. and the EU. The company's PzF coated embolic microspheres product line was sold to Boston Scientific in 2015 and the COBRA PzF NanoCoated Coronary Stent, was developed to safely and effectively treat patients who may benefit from 1-month of dual antiplatelet therapy. CeloNova's new business direction builds upon the successful application of PzF in interventional oncology and cardiology and expands its opportunities through the development of new surface coating technologies to address important unmet clinical needs. "In my pre-clinical research at CVPath since 2012, CeloNova's proprietary Polyzene-F coating has consistently demonstrated a unique advantage of allowing an implant to heal quickly and in a functional way, without the need for antiproliferative drug elution," stated Aloke Finn, MD, Medical Director and Chief Scientific Officer at CVPath and Associate Professor of Medicine at the University of Maryland. "I believe Polyzene-F will continue to play an important role in delivering safety and efficacy in clinical practice." Polyzene-F is a proprietary, ultra-pure and highly elastic surface coating possessing unique mechanical properties that allow an implant to be coated at a nanoscale level. The coating acts as a biocompatible barrier between the implant, intimal surface and circulating elements in the blood and has demonstrated thromboresistant and anti-inflammatory properties with significantly faster, higher quality healing compared to market-leading technologies.1* About CeloNova BioSciences, Inc. CeloNova BioSciences, Inc. is a global medical device company that develops, manufactures and markets novel surfaced coated technologies, including its proprietary Polyzene™-F nanocoating. The next generation nanocoating is the result of years of rigorous scientific research and engineering and has been extensively published in numerous academic articles to date.

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Spotlight

The pandemic hit the healthcare industry hard, but it also weakened the cybersecurity defenses of most providers, making them far more vulnerable to threats such as ransomware. This report, covered across national news, is considered the most significant actionable cybersecurity research over the past several years because it also documents the severe impact on patient care. This executive summary includes critical areas that providers can address starting today.

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