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Could hormone infusions help people with obesity shed weight?

August 09, 2019 / Catharine Paddock

A small-scale trial explored the effects of 4 weeks of daily hormone infusions on people with obesity and type 2 diabetes or prediabetes. The infusions lasted for 12 hours per day and contained three gut hormones, the levels of which increase in people who undergo gastric bypass surgery. The hormone combination has the name GOP, which is short for glucagon-like peptide 1, oxyntomodulin, and peptide YY . Obesity used to be a public health concern that only affected high-income nations. However, according to the World Health Organization (WHO), rates of obesity and excess weight are also increasing in middle- and low-income countries.