Nationwide digital healthcare platform soon

timesofindia | May 06, 2016

NEW DELHI: Moving towards digitisation of healthcare, the health ministry has worked out a detailed e-health project under digital India initiative of the government. The project would include hospital information system, electronic health record facilitated with health information exchange, online delivery of services, citizen portal, online monitoring systems for services and others, health minister JP Nadda informed the Lok Sabha on Friday.

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The Emory Department of Urology is leading the way in the treatment of kidney cancers, treating the smallest to the most advanced tumors. Our physicians provide expertise in focally treating kidney tumors while sparing the healthy portion of the kidney. Avoiding the removal of the entire kidney lessens the chance of kidney failure and other complications after surgery.

Spotlight

The Emory Department of Urology is leading the way in the treatment of kidney cancers, treating the smallest to the most advanced tumors. Our physicians provide expertise in focally treating kidney tumors while sparing the healthy portion of the kidney. Avoiding the removal of the entire kidney lessens the chance of kidney failure and other complications after surgery.

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HEALTH TECHNOLOGY

NVIDIA Launches UK’s Most Powerful Supercomputer, for Research in AI and Healthcare

NVIDIA | July 07, 2021

NVIDIA today officially launched Cambridge-1, the United Kingdom’s most powerful supercomputer, which will enable top scientists and healthcare experts to use the powerful combination of AI and simulation to accelerate the digital biology revolution and bolster the country’s world-leading life sciences industry. Dedicated to advancing healthcare, Cambridge-1 represents a $100 million investment by NVIDIA. Its first projects with AstraZeneca, GSK, Guy’s and St Thomas’ NHS Foundation Trust, King’s College London and Oxford Nanopore Technologies include developing a deeper understanding of brain diseases like dementia, using AI to design new drugs and improving the accuracy of finding disease-causing variations in human genomes. Cambridge-1 brings together decades of NVIDIA’s work in accelerated computing, AI and life sciences, where NVIDIA Clara™ and AI frameworks are optimized to take advantage of the entire system for large-scale research. An NVIDIA DGX SuperPOD™ supercomputing cluster, it ranks among the world’s top 50 fastest computers and is powered by 100 percent renewable energy. “Cambridge-1 will empower world-leading researchers in business and academia with the ability to perform their life’s work on the U.K.’s most powerful supercomputer, unlocking clues to disease and treatments at a scale and speed previously impossible in the U.K.,” said Jensen Huang, founder and CEO of NVIDIA. “The discoveries developed on Cambridge-1 will take shape in the U.K., but the impact will be global, driving groundbreaking research that has the potential to benefit millions around the world.” Cambridge-1 builds on the U.K.’s status as a global leader in life sciences, technology and AI by providing advanced infrastructure for current and future generations to carry out groundbreaking research within the country. According to a report by Frontier Economics, an economics consulting firm, Cambridge-1 has the potential to create an estimated value of £600 million (about $825 million) over the next 10 years. AstraZeneca: Transforming Drug Discovery with AI NVIDIA is collaborating with AstraZeneca to fuel faster drug discoveries by creating a transformer-based generative AI model for chemical structures. Transformer-based neural network architectures, which have become available only in the last several years, allow researchers to leverage massive datasets using self-supervised training methods, avoiding the need for manually labeled examples during pre-training. The MegaMolBART drug discovery model is being used in reaction prediction, molecular optimization and de novo molecular generation and will optimize the drug development process. It is based on AstraZeneca’s MolBART transformer model and is being trained on the ZINC chemical compound database — using NVIDIA’s Megatron framework to enable massively scaled-out training on supercomputing infrastructure. This open-source model will be available to researchers and developers in the NVIDIA NGC™ software catalog. NVIDIA and AstraZeneca have a separate project on Cambridge-1 focused on the use of AI in digital pathology. In digital pathology, significant time and money are spent annotating whole slide images of tissue samples, to aid the search for new insights. By using unsupervised AI algorithms trained on thousands of images, it is possible to remove the process of annotating while simultaneously finding potential imaging features that correlate with drug response. “Training AI algorithms on whole slide images is challenging in part due to the size of the images,” said Lindsay Edwards, vice president of Data Science and AI, Respiratory and Immunology, BioPharmaceuticals R&D at AstraZeneca. “Working with NVIDIA on Cambridge-1 enables us to scale our current work and develop new methodologies advancing the use of AI in digital pathology.” GSK: Steering Great Science with Partners for Patients GSK’s research and development approach includes a focus on genetically validated targets, which are twice as likely to become medicines and now make up more than 70 percent of its research pipeline. To maximize the potential of these insights, GSK has built state-of-the-art capabilities at the intersection of human genetics, functional genomics, and artificial intelligence and machine learning. “Advanced technologies are core to GSK’s R&D approach and help to unlock the potential of large, complex data through predictive modeling at new levels of speed, precision and scale,” said Dr. Kim Branson, senior vice president and global head of AI-ML at GSK. “We are pleased to have the opportunity to partner with NVIDIA to deliver on GSK’s drug discovery ambition and contribute to the U.K.’s rich life sciences ecosystem — both aims that have patient benefit at the centre.” Working with partners at the cutting edge of genetics, genomics and AI/ML can ultimately help GSK predict more about human health, and develop better medicines that are twice as likely to succeed in the clinic and go on to become approved therapies that benefit patients. Access to Cambridge-1 will contribute additional computational power and state-of-the-art AI technology to GSK’s drug discovery process. King’s College London & Guy’s and St Thomas’ NHS Foundation Trust: AI-Generated Synthetic Brain Data King’s College London and Guy’s and St Thomas’ NHS Foundation Trust are using Cambridge-1 to teach AI models to generate synthetic brain images by learning from tens of thousands of MRI brain scans, from various ages and diseases. The ultimate goal is to use this synthetic data model to gain a better understanding of diseases like dementia, stroke, brain cancer and multiple sclerosis and enable earlier diagnosis and treatment. As this AI synthetic brain model can generate an infinite amount of never-seen brain images with chosen characteristics (age, disease, etc.), it will allow a better and more nuanced understanding of what diseases look like, possibly enabling an earlier and more accurate diagnosis. “Through this partnership, we will be able to use a scale of computational power that is unprecedented in healthcare research,” said Professor Sebastien Ourselin, head of the School of Biomedical Engineering & Imaging Sciences at King’s College London. “It will be truly transformational for the health and treatment of patients.” This research leverages several of the U.K.’s world-leading healthcare resources through close collaboration with the National Health Service and the UK Biobank, one of the richest biomedical databases in the world. King’s College London intends to share this synthetic data model with the greater research and startup community. “The power of artificial intelligence in healthcare will help to speed up diagnosis for patients, improve services such as breast cancer screening, and support the way that we risk assess and prioritize patients according to clinical need,” said Professor Ian Abbs, chief executive officer of Guy’s and St Thomas’ NHS Foundation Trust. “We are excited about our involvement in the Cambridge-1 data center as it will enable us to be amongst the first to benefit from these new AI capabilities — using the very latest technology to benefit our patients, as well as manage precious resources more efficiently.” Oxford Nanopore: Scalable, Real-Time Genomics Oxford Nanopore Technologies’ long-read sequencing technology is being used in more than 100 countries to gain genomic insights across a breadth of research areas — from human and plant health to environmental monitoring and antimicrobial resistance. Oxford Nanopore deploys NVIDIA technology in a variety of genomic sequencing platforms to develop AI tools that improve the speed and accuracy of genomic analysis. With access to Cambridge-1, Oxford Nanopore will be able to carry out tasks relating to algorithm improvement in hours rather than days. These improved algorithms will ensure improved genomic accuracy for greater insights and quicker turnaround times in scientists’ hands. “Harnessing the power of Cambridge-1 will help us further speed up our algorithm development to support powerful, accurate genomic analysis,” said Rosemary Sinclair Dokos, vice president of Product and Programme Management at Oxford Nanopore. “This will in turn enable the scientists using our technology on the ground to gain more insights than ever before, across a breadth of research areas.” About Cambridge-1 Cambridge-1 is the first NVIDIA supercomputer designed and built for external research access. The company will collaborate with researchers to make much of this work available to the greater scientific community. About NVIDIA NVIDIA’s (NASDAQ: NVDA) invention of the GPU in 1999 sparked the growth of the PC gaming market and has redefined modern computer graphics, high performance computing and artificial intelligence. The company’s pioneering work in accelerated computing and AI is reshaping trillion-dollar industries, such as transportation, healthcare and manufacturing, and fueling the growth of many others.

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HEALTH TECHNOLOGY

Invitae to Acquire Ciitizen to Strengthen its Patient-Consented Health Data Platform to Improve Personal Outcomes and Global Research

Invitae | September 07, 2021

Invitae, a leading medical genetics company, today announced it has entered into a definitive agreement to acquire Ciitizen, a patient-centric consumer health tech company. Backed by a16z, Section 32 and Verily, Ciitizen is working to build a global platform to help patients collect, organize, store and share their medical records digitally. The acquisition would enhance Invitae's platform by providing patients an easy-to-use, centralized hub for their genomic and clinical information, which together comprise a powerful dataset with the potential to drive research and improve healthcare decision making. "Invitae is relentlessly pursuing a day when genetics is used routinely to improve healthcare for billions of people around the globe. We believe combining Ciitizen's state-of-the-art, transparent and patient-consented platform with our technologies and services will accelerate our evolution into a genome information company that informs healthcare throughout one's life. This would give us the ability to engage patients, create an innovative patient-centered data ecosystem and deliver better outcomes for everyone. Invitae views the acquisition of Ciitizen as an important part of its strategy to be the industry leader across the genetic testing, software and health information technology spaces," said Sean George, Ph.D., co-founder and CEO of Invitae. "Ciitizen has already helped patients take ownership of their medical records to optimize therapy for themselves and contribute their data towards a variety of goals, including research on rare diseases," said Anil Sethi, CEO and founder of Ciitizen. "Patients leave a breadcrumb trail of records behind them, and we believe access to this real-world data is key to personalized therapeutics in the future. The combination of lifelong health history together with Invitae's world-class genetic and data services would enable a digital ecosystem of personalized services for each patient. Democratization of patient-consented data is expected to improve outcomes by providing access to third-parties for whom the patient has granted consent. Unlike many health data companies, we operate on the premise that it's the patient's data, not ours." Dr. George continued, "Genomics is currently a laboratory testing-based industry, but in the future it will look very much like an information industry. Developing an open-ended patient-centric platform of genomic, clinical and reported outcomes creates a thriving and purposeful network that truly advances healthcare. Patient control is the big differentiator at Ciitizen and at Invitae; and we believe combining forces is the right strategy for our businesses going forward." Empowering patients to combine their genomic and clinical information to improve clinical care Invitae is working to aggregate results from the world's genetic tests into a single, easy-to-use service that makes genetic information accessible to all who can benefit from it - always with patient consent. Over the past five years, Invitae has completed 13 acquisitions that have expanded its testing menu, lowered the cost of its tests, improved its customer experience and enhanced its ability to attract partners. Invitae raised more than $1.4 billion since the beginning of 2021, in part to identify and acquire key assets that bring the company closer to delivering on its vision. The addition of Ciitizen is expected to empower Invitae to more quickly extend its platform, adding a complementary patient service that streamlines the process of collecting and organizing health information from any source and uses machine learning to transform the unstructured (and largely untapped) health information to enable better care decisions, find clinical trials, and power research using real-world evidence. In addition, as the use of Invitae testing and the Ciitizen service expands, third-party access to consented genomic and other clinical data can be democratized to power a variety of applications that can enhance Invitae's business and growth strategy. Transaction Terms Under the terms of the agreement, Invitae will acquire Ciitizen for approximately $325 million (subject to adjustment), consisting of (i) approximately $125 million in cash and (ii) approximately 7,070,000 shares of Invitae common stock (based upon a trailing average closing price prior to the agreement date). Invitae will also issue approximately $225 million in restricted stock units (RSUs) to new employees who join Invitae in connection with its acquisition of Ciitizen. These RSUs will be granted under Invitae's 2015 Stock Incentive Plan, which is being amended and restated to increase a pool of shares of Invitae common stock thereunder which is used exclusively for the grant of inducement awards in compliance with New York Stock Exchange Rule 303A.08 ("Rule 303A.08"). These RSUs have been approved by the Invitae Board of Directors and will be made as an inducement material to each employee entering into employment with Invitae in reliance on the employment inducement exemption under Rule 303A.08. These RSUs will cover up to a total of approximately 8,125,000 shares of Invitae common stock (based upon a trailing average closing price prior to the agreement date) and will vest in tranches of one-third upon each of the first, second and third anniversaries of the date of grant, subject to acceleration in the event of a termination without cause by Invitae or a termination with good reason by a recipient. A total of 99 recipients will receive these RSUs, and Anil Sethi, the CEO and founder of Ciitizen, will receive RSUs with respect to approximately 2,011,000 shares of Invitae common stock. The transaction, which has been unanimously approved by the Boards of Directors of both companies, is expected to close this month. Conference Call and Webcast today at 8:30 a.m. ET / 5:30 a.m. PT Management will host a conference call and webcast today at 8:30 a.m. ET / 5:30 a.m. PT to discuss the transaction. To register for the conference call, please use the link below. Upon registering, each participant will be provided with call details and a registrant ID. The live webcast of the call and slide deck may be accessed here or by visiting the investors section of the company's website at ir.invitae.com. A replay of the webcast and conference call will be available shortly after the conclusion of the call and will be archived on the company's website. About Invitae Invitae Corporation is a leading medical genetics company, whose mission is to bring comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Invitae's goal is to aggregate the world's genetic tests into a single service with higher quality, faster turnaround time, and lower prices. About Ciitizen Ciitizen is a patient-centric consumer health technology platform that enables patients to collect, store and share their medical records in a single location. Ciitizen developed proprietary machine learning and AI technologies to abstract critical information from unstructured health records to advance the understanding of diseases, match patients with potentially life-saving clinical trials, and enable better care decisions. Ciitizen also provides valuable big data analytics and data quality technologies to the network of Health Information Exchanges (HIEs) to produce research-ready, regulatory-grade data within minutes, instead of hours or days, and ensure HIEs can comply with the Information Blocking regulations.

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HEALTH TECHNOLOGY

MyndVR and Omega Healthcare Announce a Strategic Alliance to Deliver Virtual Reality Therapeutics in Senior Care

MyndVR | March 01, 2022

MyndVR, the leading provider of Virtual Reality ("VR") solutions for senior care today announced a strategic partnership withOmega Healthcare Investors. As one of the largest REITs in senior care, Omega is committed to bringing technology and innovation to its expanding base of operators across the continuum of care in the US and UK. Omega will make MyndVR's industry-leading portfolio of senior-friendly, therapeutic VR experiences available to nearly 1000 senior living and skilled nursing facilities. This 3-year partnership will offer Omega's valued operators access to MyndVR's vast network of immersive content, state-of-the-art VR headsets, and proprietary care tablets, as the exclusive VR partner of Omega with pricing promotions to all Omega operators. The MyndVR platform includes a bundled subscription plan with monthly content updates across a wide variety of reminiscence, music, art, nature-immersion, meditation, and cognitive programs to help seniors achieve their skilled therapeutic goals. Taylor Pickett, Omega's Chief Executive Officer, stated, "We are excited to partner with MyndVR and align our concurrent missions of improving the lives of older adults.We look forward to helping senior care centers deploy this highly engaging and outcome-focused technology." At a time when the entire senior living industry is looking for easy-to-administer, time-saving activities that enrich the daily lives of seniors, virtual reality has become a very affordable and highly researched therapeutic tool. "We are deeply committed to providing VR-based therapeutic solutions that involve interactive content, sensory technology, and measurable outcomes. We are thrilled to partner with Omega to expand our reach and scale in improving the lives of hundreds of thousands of seniors." Chris Brickler, CEO and co-founder of MyndVR MyndVR serves several hundred senior communities across 45 states,CanadaandAustralia. Sodalis Senior Living has successfully rolled out MyndVR in 26 communities acrossTexasandFlorida. "At Sodalis, we have seen an immediate improvement in resident socialization after using MyndVR, as well as an increase in activity engagement with staff," saidTraci Taylor-Roberts, President at Sodalis Senior Living. "It's exciting because VR represents a game-changing approach to delivering activities and therapies for our residents." About Omega Healthcare Investors Omega Healthcare Investors is a real estate investment trust that invests in the long-term healthcare industry, primarily in skilled nursing and assisted living facilities. Its portfolio of assets is operated by a diverse group of healthcare companies, predominantly in a triple-net lease structure. The assets span all regions withinthe United States, as well as in theUnited Kingdom. About MyndVR MyndVR is the leading provider of Virtual Reality solutions for senior living communities, home health care agencies, Veteran homes, and individual adults aging in their own homes. The company has built a vast network of original and licensed therapeutic VR content. Their technology enables older adults to interact with the outside world in genuinely innovative ways that promote engagement, wellness, and above all, positive outcomes. MyndVR is committed to continued research and development to measure outcomes, including cognitive, visual, emotional, and physical effects on older adults.

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