Hospitals Slashed Use Of Two Heart Drugs After Huge Price Hikes

Kaiser Health News | August 09, 2017

Even before media reports and a congressional hearing vilified Valeant Pharmaceuticals International for raising prices on a pair of lifesaving heart drugs, Dr. Umesh Khot knew something was very wrong. Khot is a cardiologist at the Cleveland Clinic, which prides itself on outstanding heart care. The health system’s pharmacists had alerted doctors about the skyrocketing cost of the drugs, nitroprusside and isoproterenol. But these two older drugs, frequently used in emergency and intensive care situations, have no direct alternatives.

Spotlight

Stress is the way our bodies and minds react to a particular challenge or situation. By recognizing the signs and symptoms of stress, you can help your child learn to manage his or her responses in a healthier way.

Spotlight

Stress is the way our bodies and minds react to a particular challenge or situation. By recognizing the signs and symptoms of stress, you can help your child learn to manage his or her responses in a healthier way.

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HEALTH TECHNOLOGY

Smith+Nephew introduces smart glasses into the operating room to enable remote technical support for UK surgeons during procedures

Smith & Nephew | July 11, 2022

Smith+Nephew the global medical technology company, announces a partnership with Rods&Cones to provide smart surgery glasses and digital remote assistance to customers. By providing customers with smart surgery glasses, Smith+Nephew representatives can 'see' through the eyes of the surgeon, instrumentalist nurse, or any healthcare professional using them, enabling continuous remote support before, during, and after surgical interventions. Initially used in the UK to support the NHS and other customers, this solution allows Smith+Nephew to increase its ability to offer technical support for safe and effective use of its products at the right time from anywhere in the world. The increased complexity of surgery, advancement of technologies, and need for productivity and efficiency is enabled by ensuring a specialist is available remotely to give best possible expertise exactly when they need it, in the least disruptive way. "I am delighted that we have agreed to partner with one of the most innovative companies in the area of remote surgical support," said Simon Tarry, Managing Director of Smith+Nephew's UKI/Nordics region. "This new partnership will enable our team to deliver the highest possible expertise exactly when our customers and patients need it. At the same time, I believe enhancing our ability to support our customers remotely serves patient safety and sustainability to great effect." The multi-year agreement with Rods&Cones allows Smith+Nephew to scale its remote support capability for customers, enabling connectivity with specialist surgeons during minimally invasive surgery. The MIS Kit connects seamlessly to a secure Rods&Cones Remote Expert interface, which allows the user to follow and attend a surgery just as if standing in the OR, but with the exact view of the surgeon or other healthcare professional. "We are thrilled to work with such a great company as Smith+Nephew. The achievements they have made in the MedTech industry, especially within the sphere of repair, regeneration and replacement of soft and hard tissue has been awe-inspiring. This partnership between Smith+Nephew and Rods&Cones will be a great step forward and together we will change healthcare for the better." Bruno Dheedene, CEO and Founding Partner of Rods&Cones About Smith+Nephew Smith+Nephew is a portfolio medical technology business focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people's bodies and their self-belief by using technology to take the limits off living. We call this purpose 'Life Unlimited'. Our 18,000 employees deliver this mission every day, making a difference to patients' lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global franchises of Orthopaedics, Sports Medicine & ENT and Advanced Wound Management. Founded in Hull, UK, in 1856, we now operate in more than 100 countries, and generated annual sales of $5.2 billion in 2021. Smith+Nephew is a constituent of the FTSE100. The terms 'Group' and 'Smith+Nephew' are used to refer to Smith & Nephew plc and its consolidated subsidiaries, unless the context requires otherwise. About Rods&Cones Rods&Cones' purpose is to be a catalyst of change in healthcare to improve people's lives. The company provides a remote assistance service used to connect medical experts worldwide. With their state-of-the-art technological devices and a digital remote assistance platform, users can connect safely with surgeons, product specialists, or other medical professionals anywhere in the world, in real-time. Rods&Cones was founded in 2017 by two brothers, Bruno and Jan Dheedene. Based in Amsterdam, The Netherlands, the company has now become a leading international supplier of remote surgical assistance services.

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HEALTH TECHNOLOGY

Sonde Health Inks MultiYear Partnership with Koye Pharmaceuticals

Sonde Health | August 25, 2022

Sonde Health, a leading enterprise vocal biomarker company, has signed a multi-year agreement with Koye Pharmaceuticals, a specialty pharma organization focused on the Indian Pharmaceutical market, to develop a new vocal biomarker detection and monitoring capability for chronic obstructive pulmonary disease in India. This deal represents Sonde’s first partnership with a pharmaceutical company. As part of this arrangement, Koye will leverage Sonde’s vocal biomarker development (VBD) platform, expanding upon its already existing respiratory responsive vocal biomarker, to create an entirely novel vocal biomarker for COPD in India. This will allow Koye to develop solutions that help track and treat respiratory health in COPD patients using their voice. “This collaboration marks a major milestone in Sonde Health’s growth and evolution, and we’re excited to take this step with Koye Pharmaceuticals. Partnering directly with pharmaceutical companies allows them to take a more targeted and engaging approach with prospective patients, aligning their needs with the most impactful therapeutics. While there’s no cure for COPD, this new vocal biomarker will allow physicians to better manage their patients’ symptoms using early monitoring and constant engagement to ensure those impacted by COPD get on the right treatment plans early and often.” David Liu, CEO of Sonde Health COPD, a chronic inflammatory lung disease that creates airflow blockage and makes it difficult to breathe, is the third leading cause of death worldwide – causing 3.23 million deaths in 2019, according to the World Health Organization – and the second highest cause of death and disability in adjusted life years (DALYs) in India after heart disease, per the University of Washington’s Global Burden of Disease study. As of 2018, India had 18% of the world’s population, but 32% of the COPD cases. COPD was responsible for 13% of all deaths in India. A worldwide study has estimated that India’s death rate from COPD during 2019 was 98 per 100,000 population, three times the American rate of 33 and the British rate of 31. According to the latest figures, India has an estimated 50 million people living with COPD. “We have been keen on utilizing an accessible platform with digital biomarkers that will both aid physicians in identifying and understanding their patients’ conditions better and also make it easier for patients with chronic respiratory conditions to monitor their health in the least invasive way possible. This partnership with Sonde Health is exactly what we were looking for,” said Preetish Toraskar, Founder and Director at Koye Pharmaceuticals. “Not only is Sonde at the forefront of vocal biomarker technology, but their extensive experience in respiratory health will prove invaluable as we work to get this debilitating condition under control in India.” Sonde Health has previously developed and commercialized vocal biomarker technology to detect and monitor respiratory impairment. In early 2022, the company partnered with GN Group, a leading global manufacturer of hearing instruments and audiological diagnostics equipment and headsets, to create vocal biomarker technology to detect Mild Cognitive Impairment. About Sonde Health Sonde Health has developed an enterprise vocal biomarker platform that enables any company to either license respiratory or mental fitness monitoring product or create a novel vocal biomarker product. Sonde scales data collection, feature development, model creation and clinical validation in collaboration with its partners and customers. Leveraging over 1 million voice samples from 80,000+ individuals, Sonde uses advanced audio signal processing and machine learning to sense and analyze subtle vocal changes due to changes in a person’s physiology to provide key insights into health and well-being. About Koye Pharmaceuticals Koye Pharmaceuticals Pvt. Ltd. was founded in 2013 by two experienced professionals of the pharma industry, Mr. Preetish Toraskar and Mr. Ravindra Shenoy. Since its foundation, Koye has expanded its operations to run across the length and breadth of the country aided by their strong distribution network. Koye today has more than 1250+ qualified ambassadors who meet up with more than 100,000+ doctors across the country every month. The company which believes in pursuing 'healthiness' has a strong foothold in different therapeutic segments that include state-of-the-art products in Specialty Primary Care, Respiratory, Gynaecology, IVF and Cardio-Diabetic segments.

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FUTURE OF HEALTHCARE

Anumana Collaborates with Leading Global Health Care Company to Detect Heart Disease Using Artificial Intelligence

Anumana, Inc. | July 14, 2022

Anumana, Inc., an AI-driven health technology company and portfolio company of nference, has launched a multi-year strategic collaboration with Novartis Pharmaceuticals Corporation (“Novartis”) to deploy a series of artificial intelligence powered software solutions that will detect hidden cardiovascular conditions. The collaboration will drive development and delivery of electrocardiogram (ECG) AI algorithms to help physicians accelerate detection and intervention for patients with previously undetected life-threatening heart disease. The ECG AI algorithm is still in development and not yet FDA authorized for commercial clinical use. The collaboration will support Anumana’s efforts to implement AI-enabled diagnostic software that can detect signals from ECGs that humans cannot interpret. The collaboration will initially focus on cardiovascular diseases. Working with its expert partners from Mayo Clinic, Anumana will deploy novel solutions that use AI to analyze an ECG, a widely available, painless test that records the heart’s electrical signals to identify undiagnosed left ventricular dysfunction, or a weak heart pump, which can lead to heart failure. The AI will also screen for atherosclerotic cardiovascular disease, which can lead to heart attack and stroke. In addition, an evidence-based, digital point-of-care solution will be developed to guide in optimizing guideline-directed medical therapies with the aim to lower risk for potentially avoidable hospitalizations and cardiovascular death. “Anumana technology is designed to help physicians identify patients who are at maximum risk of heart failure, long before they develop symptoms. Bringing together premier global organizations will allow us to expand access to best-in-class, AI-powered digital tools to benefit patients through earlier detection and intervention, when and where health care providers need it most.” Murali Aravamudan, CEO of Anumana “Many heart diseases develop for years before signs and symptoms appear, but the first event may be life threatening,” said Paul Friedman, M.D., Chair of the Department of Cardiovascular Medicine at Mayo Clinic and Chair of Anumana’s Mayo Clinic Board of Advisors. “AI enables us to uncover hidden signals our bodies transmit to detect otherwise occult heart diseases, potentially years before symptoms appear. This collaboration has the potential to transform the use of a ubiquitous inexpensive test, the ECG, with the aim of democratizing disease detection and helping medical care teams to proactively manage heart disease ahead of time and prevent some clinical events from ever happening.” “Cardiovascular disease is a widespread and multifactorial disease and, in order to mitigate its impact, we must look beyond therapeutic innovation and reimagine how we approach cardiovascular care,” said Victor Bulto, President, Novartis Innovative Medicines US. "Novartis is proud to collaborate with Anumana on innovative and data-driven solutions to better predict the risk of life-threatening heart disease, further driving forward our commitment to improving patient experiences and population health outcomes in this patient population.” The Mayo Clinic Cardiology team, led by Dr. Friedman, pioneered the application of AI in cardiology and developed several algorithms based on millions of ECGs, including a low ejection fraction algorithm that received FDA Breakthrough Device Designation in 2019 and Emergency Use Authorization for COVID-19 in 2020. Further validating the technology, a recent study presented by Mayo Clinic used a modified version of Anumana’s 12-lead ECG algorithm to detect left ventricular dysfunction with single-lead ECGs in smartwatches. These algorithms are licensed to Anumana for development of clinical solutions and have been validated by over 30 peer-reviewed publications, including a first of its kind prospective clinical impact study on low ventricular ejection fraction that was published in Nature Medicine in 2021. These software solutions are currently in development with each algorithm as a candidate for marketing authorization through an FDA De Novo request. About Anumana Anumana, an AI-driven health technology company and a portfolio company of nference and Mayo Clinic Platform, is harnessing industry-leading AI and translational science to decode the electrocardiogram as never before – as a deep predictive tool and biomarker of disease – empowering care providers to help patients early. Anumana algorithms have been developed, trained, and validated using clinical data from Mayo Clinic and are undergoing rigorous clinical trial validation. Anumana is developing AI-enabled ECG algorithms for real-world physician use, integrating point-of-care applications into existing workflows, thereby reducing costs and enhancing quality of life. Anumana’s AI-enabled tools can diagnose hidden conditions earlier than ever before. Anumana’s algorithms are investigational medical devices and have not yet received regulatory approval or clearance.

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