We all have a role to play in driving forward mental health services

JACQUI DYER | July 14, 2015 | 147 views

I take seriously the mandate given by the people who responded to the call for evidence, by completing the online survey run by Mind and Rethink Mental Illness, or by submitting something in writing to the Mental Health Taskforce inbox. While the task is urgent and enormous – some are grumpily saying that it is impossible, even – I fundamentally believe it is absolutely possible to transform mental health outcomes across the NHS.

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Alira Health

Alira Health is an international patient-centric and technology-enabled advisory firm whose mission is to humanize healthcare. We work with healthcare and life sciences organizations looking for support across their entire solutions lifecycle, from development to medical care, through real-world evidence.

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HEALTH TECHNOLOGY

Why the future of healthcare is (mostly) in the cloud

Article | August 12, 2022

Healthcare leaders are embracing the benefits of the cloud and software as a service (SaaS) after the pandemic challenged them to adapt and innovate like never before. 66% of them expect to move their technology infrastructures to the cloud this year – a number that is set to rise to 96% by 2024 [1]. Yet moving to the cloud is more than just a technology transformation. It’s an organizational transformation. Through cloud-based platforms and solutions, healthcare systems can begin to unlock clinical and operational insights at scale while speeding up innovation cycles for continuous value delivery. Integrating data across the care continuum In many ways, COVID-19 catapulted healthcare into the future. The pandemic created a new urgency for healthcare leaders to expand their virtual care offerings as a way of connecting with patients beyond the walls of the hospital. At the same time, they wanted the flexibility to scale up or down without large upfront capital expenditures. Effective crisis management also required the rapid exchange of patient information across systems and care settings. Thanks to the flexibility of pay-as-you-go cloud-based services and solutions, healthcare providers were able to quickly scale up digital health technologies to meet new demands. As a result, the acceptance of cloud has increased remarkably [2]. Keeping patient data secure and compliant As healthcare leaders embark on this journey to the cloud, data protection is a critical consideration. Data processing in healthcare must comply with rigorous standards, whether it is HIPAA in the US or GDPR in the EU. Unfortunately, healthcare organizations also remain a top target for data breaches, calling for additional data security protection measures [3]. While the need for data security and regulatory compliance has historically motivated healthcare organizations to keep data on premises, today there is a growing awareness that moving to the cloud can in fact be the better road to travel. In fact, 60% of healthcare leaders now cite security as one of the top benefits of the cloud [4]. When healthcare organizations rely on their own data centers, they are responsible for security from end to end, which can become prohibitively complex and time-consuming as IT infrastructures expand over time. Cloud-based services and solutions can reduce dependency on local hardware to store sensitive data while automated software updates keep systems current. Turning data into insights at scale at the point of care Working from these foundations, the next big opportunity in healthcare is to capture the insights in the data that we are beginning to connect and integrate. This is where the cloud is also turning into a vital enabler, with its powerful computing resources and advanced machine learning capabilities, offered as microservices. These microservices provide the building blocks to develop new digital solutions that, once validated and approved, can be deployed at scale to help improve clinical outcomes and operational efficiency. Enabling rapid experimentation and continuous value delivery Embracing the cloud also changes the very nature of innovation in healthcare. Healthcare-compliant cloud platforms offer a flexible foundation for rapid development and testing of digital applications. Cross-functional teams working in short and agile cycles can put new digital applications into the hands of physicians or patients more quickly, and then add new or improved features and functionalities as they gather additional user feedback. That means healthcare organizations get to innovate faster. And in smaller, more digestible increments. Moving to the cloud is not all or nothing Of course, none of this is to suggest that moving to the cloud is like switching a button. It’s a complex and multi-year journey for most of our customers. And it’s quite a journey for Philips, too. Any organization that has accumulated a large number of legacy systems and infrastructures over the years will have to manage a hybrid architecture during their journey to the cloud [5].

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DIGITAL HEALTHCARE

The digital hospital of the future

Article | June 4, 2022

​As the cost of care continues to rise, many hospitals are looking for long-term solutions to minimize inpatient services. Learn how technology and health care delivery will merge to influence the future of hospital design and the patient experience across the globe in this report developed by Deloitte US. Five use cases for the digital hospital of the future The future of health care delivery may look quite different than the hospital of today. Rapidly evolving technologies, along with demographic and economic changes, are expected to alter hospitals worldwide. A growing number of inpatient health care services are already being pushed to home and outpatient ambulatory facilities. However, many complex andv very ill patients will continue to need acute inpatient services. With aging infrastructure in some countries and increased demand for more beds in others, hospital executives and governments should consider rethinking how to optimize inpatient and outpatient settings and integrate digital technologies into traditional hospital services to truly create a health system without walls. To learn what this future of health care delivery may look like, the Deloitte Center for Health Solutions conducted a crowdsourcing simulation with 33 experts from across the globe. Participants included health care CXOs, physician and nurse leaders, public policy leaders, technologists, and futurists. Their charge was to come up with specific use cases for the design of digital hospitals globally in 10 years (a period that can offer hospital leaders and boards time to prepare). The crowdsourcing simulation developed use cases in five categories Redefined care delivery Emerging features including centralized digital centers to enable decision making (think: air traffic control for hospitals), continuous clinical monitoring, targeted treatments (such as 3D printing for surgeries), and the use of smaller, portable devices will help characterize acute-care hospitals. Digital patient experience Digital and artificial intelligence (AI) technologies can help enable on-demand interaction and seamless processes to improve patient experience. Enhanced talent development Robotic process automation (RPA) and AI can allow caregivers to spend more time providing care and less time documenting it. Operational efficiencies through technology Digital supply chains, automation, robotics, and next-generation interoperability can drive operations management and back-office efficiencies. Healing and well-being designs The well-being of patients and staff members—with an emphasis on the importance of environment and experience in healing—will likely be important in future hospital designs. Many of these use-case concepts are already in play. And hospital executives should be planning how to integrate technology into newly-built facilities and retrofit it into older ones. Technology will likely underlie most aspects of future hospital care. But care delivery—especially for complex patients and procedures—may still require hands-on human expertise. Laying the foundation for the digital hospital of the future ​Building a digital hospital of the future can require investments in people, technology, processes, and premises. Most of these investments will likely be upfront. In the short term, hospital leadership may not see immediate returns on these investments. In the longer term, however—as digital technologies improve care delivery, create operational efficiencies, and enhance patient and staff experience—the return result can be in higher quality care, improved operational efficiencies, and increased patient satisfaction. These six core elements of an enterprise digital strategy can help you get started as you begin to push your hospital into the future Create a culture for digital transformation It is essential that senior management understands the importance of a digital future and drives support for its implementation at all organizational levels. Consider technology that communicates Digital implementation is complex. Connecting disparate applications, devices, and technologies—all highly interdependent—and making certain they talk to each other can be critical to a successful digital implementation. Play the long game Since digital technologies are ever evolving, flexibility and scalability during implementation can be critical. The planning team should confirm that project scope includes adding, modifying, or replacing technology at lower costs. Focus on data While the requirements of data interoperability, scalability, productivity, and flexibility are important, they should be built upon a solid foundation of capturing, storing, securing, and analyzing data. Prepare for Talent 2.0 As hospitals invest in exponential technologies, they should provide employees ample opportunities to develop corresponding digital strategies. Maintain cybersecurity With the proliferation of digital technologies, cyber breaches can be a major threat to hospitals of the future. Executives should understand that cybersecurity is the other half of digital implementation and allocate resources appropriately.

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HEALTH TECHNOLOGY

AI in Healthcare Businesses: From Efficient Uses Cases to ROI Growth

Article | May 30, 2022

It’s no secret now that healthcare is an in-demand field. Today, business leaders need modern and intelligent decision-making solutions for their customers and clients. They must also focus on the right investment areas and learn the tricks for investing, spending, and setting goals for revenue generation to accelerate business. With continuous developments in the healthcare sector, integrating AI into processes can help increase ROI. Therefore, if you, like any other business leader, are looking for solutions to empower your services and products in the healthcare domain, this article will help you through AI’s ultimate use cases and churn out a higher ROI. What’s with AI in Healthcare at Present? AI’s role in healthcare is evolving and enhancing traditional business operations, particularly marketing. According to a study by IBM, 71% of customers expect real-time communication. Thus, global demand is fueling the rising adoption of AI marketing solutions. The effects of AI in healthcare are evident. Gartner reports increased marketing efficiency and effectiveness (86%), improved decision-making (71%), better data analysis and new insights (79%). Global AI spending will rise from $450 million in 2019 to over $28 billion by 2024 is not surprising. Similar and further studies are ongoing on various use cases of AI in healthcare at scale. What are the efficient use cases of AI that will help healthcare businesses boost their ROI? Let’s find out. How is AI Applied in Healthcare? The promising applications of AI in healthcare to improve outcomes are very intriguing. While there is still much to achieve in the AI-dependent healthcare business, there is sufficient potential that tech companies are willing to invest in AI-powered tools and solutions. Let’s examine the potential examples of AI in healthcare to prepare and support business strategies accordingly and foster higher ROI generation. Predictive Analytics AI-based predictive analytics impacts a business by automating administrative tasks, predicting sales outcomes for a year, customers’ behavior and making strategies accordingly. According to a Forbes study, AI-based predictive analytics can save businesses $18 billion in tasks, expenses, and pricing. To understand this, one example of using AI to automate admin tasks is a collaboration between the Cleveland Clinic and IBM. Cleveland Clinic uses IBM’s Watson to mine big data and provides personalized services for customers and clients on marketing deeds. Some of the practical applications of AI and predictive analytics in healthcare are: Monitoring market trends to maximize marketing efforts Organizing datasets Creating marketing campaigns tailored to each demographic-based client Mining collective data for future decision-making Fraud Prevention AmerisourceBergen Corp detects fraud and misleading business operations through AI. A sales account team conducts audits with AI to detect usual lea and queries to prevent hefty expenses for businesses. The example explains that implementing AI in your process will help detect any significant fraud attempts inside your business operation. This will help your business save huge expenditures. Boost Sales By putting down false leads, AI helps in maximizing sales numbers, resulting in significant ROI generation. For example, AI transforms data into personalized data, which reduces the cost of operations. Chatbots Most healthcare businesses leverage chatbots on their websites to engage more and more customers and boost engagement. In this way, businesses tend to gain multiple leads and convert them into clients by providing the best marketing solutions. Chatbots are fruitful for AI start-ups in healthcare—small businesses can deploy AI to their websites. By doing so, they can save millions in administrative costs and attract numerous leads. The most prominent examples of AI in healthcare hail from giant tech titans such as IBM, Amazon, and Microsoft. They are assisting healthcare providers with AI to create and deploy digital-human employees. Segmentation of Marketing Targets Is your target audience not responding to your marketing campaigns (for example, by not clicking a link, subscribing or unsubscribing to a newsletter, or not registering for a medical event)? If that's the case, how should you go ahead? Using AI-based tools allows your marketing to easily identify target behaviors and reactions based on the type of marketing actions to be carried out. Analyzing these actions can help segment targets based on your company's marketing objectives. The most significant development took place in April 2022, when Amazon Alexa became fully HIPAA compliant. It works with health developers and service providers that manage protected information for customers. AI Leads to Data Modernization It’s all about the data—not any data! There’s a precise association between AI and data management, resulting in data modernization. According to a Cognizant research study, healthcare leaders have made significant progress in modernizing their data. In contrast, most upcoming businesses are expecting to do so by 2024. The maximum acceleration of AI in modernizing data will be seen in the manufacturing and marketing of healthcare products and services, respectively. It is because AI helps to churn data easily. The accessibility of data, in particular, becomes simpler with automation than doing it manually, which generates a massive amount of data. Such effects of AI in healthcare can be one of the prime reasons for the higher ROI of your business in the future. “There has never been a greater need for skilled analytic talent in health care. Because AI is becoming more strategic, organizations must ensure access to this skill set, either by growing their analytic teams or seeking out experienced partners." Steve Griffiths, CEO of Optum Enterprise Analytics AI Expenditure is on the Rise McKinsey says that by 2025, the use of AI in healthcare will be widespread, resulting in significant expenditure by global healthcare leaders. AI is a significant concern for healthcare decision-makers, investors, and innovators as customers extensively engage and react to AI-powered services and solutions. AI is constantly bringing improvements to almost all processes, including cost savings, management of services and products, and monitoring of multiple operations. Even small businesses in the healthcare industry are proactively investing in AI applications to match steps with the current wave of innovation in healthcare services. Accelerate ROI Using AI AI in healthcare is becoming one of the prime responsible technologies for accelerating ROI. Technology can eradicate multiple business growth challenges. Let’s find out how. Enhanced Performance As previously stated, use cases of AI in healthcare can relieve stress on employees. This would allow them to devote their time to more value-added marketing activities to churn more ROI. Emphasize Cost-Effectiveness Most of the businesses associated with healthcare are concerned about the costs involved. With AI, they now develop policies to spend less on non-essential activities and necessitate profit-oriented actions. "We believe in the potential of AI to deliver insights and operational efficiencies that unlock better health-care performance." Robert Musslewhite, CEO at OptumInsight Frequently Asked Questions How is AI used in healthcare? AI in healthcare automates and predicts processes by analyzing data throughout. It is used to predict potential customers, improve business management workflows, and manufacture medical products. How does AI drive growth in the healthcare industry? AI drives business growth by improving the ability to understand better day-to-day customer patterns and needs based on services and products. How is AI changing the Healthcare industry? AI applications in healthcare have demonstrated their potential to improve analytics and data management and assist service providers in making timely medical decisions.

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HEALTH TECHNOLOGY

Wearable Technology is the New Healthcare!

Article | May 18, 2022

Do you know you can now wear technology? With the help of wearable technology, it's now easier to keep track of useful information in one go! This go-to technology has made people’s lives easier and smoother health-wise. In the last five years, more people have started using wearable technology to monitor health data and live healthier lifestyles. According to the Deloitte Global Survey, today, more than 80% of people are interested in using wearable technology. Statista also studied that the ear-worn wearable technology market will be worth more than 44.16 billion US dollars by 2023. These data show that customers are gravitating toward wearable technology due to its simplicity and convenience. The Tech is Getting Smarter Wearable technology has enabled the concept of self-checking, evaluation and monitoring of certain health conditions. The Internet of Things (IoT) technology is transforming and improving the entire lifestyles of millions of people. So it's no surprise that the technology is spreading. Thanks to IoT and AI, which have pushed these technologies into individuals’ hands in the form of smartwatches, fitness bands, and other devices. In this case, app development has also been a critical success factor. Consumers of all age groups actively use wearable technology for multiple physical benefits, such as monitoring daily activities (running, walking), water intake, heartbeat, sleep cycles, blood pressure, oxygen level, and mobility levels. In fact, the tech helps them to stay motivated by maintaining and extending their good habits. Wearables can measure these characteristics through an effective data model that is instantly responsive. The readings can be saved, displayed, or forwarded to a doctor for medical study. This interface of wearable technology saves money and time traveling to clinics, hospitals, GPs, and other medical facilities. The next feature that only wearable technology provides is reminders and inspiring information! Due to the addition of automatic functionalities, users have invested considerably in wearables and sparked the usage at the current time. Furthermore, wearable technology is also seen in other medical devices such as ECG monitors, which is again a cutting-edge consumer electronic device that users can use to measure electrocardiograms at home. A Deloitte study found that due to the rising demand and supply together, nearly 200 million wearable gadgets will be marketed globally by 2023. Transforming Healthcare Towards Intelligence The pandemic accentuated the importance of wearable technology the most, particularly for health monitoring. As a result, the technology was available in every second home. Wearable innovation is exceptional with the advancements in sensors, artificial intelligence, machine learning, and algorithms. Sensor data provides insights regarding an individual's activity levels, cardiac pattern discrepancies, and other aspects. For example, many companies and manufacturers employ PPG, Raman spectroscopy and infrared spectrophotometers to enable blood pressure monitoring features in smartwatches and portable medical devices. The combination of technology with intelligence is creating a whole new world of healthcare where individuals can track, record, and improve their health issues in a lesser timeframe. A Committed Future of Healthcare So, will technology for health improvement thrive? The answer is yes. Wearable technology delivers real-time health data and allows consumers to improve their health without incurring high costs. Consumers' willingness to share their data with healthcare professionals indicates a surge in future demand for wearable technology gadgets.

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Spotlight

Alira Health

Alira Health is an international patient-centric and technology-enabled advisory firm whose mission is to humanize healthcare. We work with healthcare and life sciences organizations looking for support across their entire solutions lifecycle, from development to medical care, through real-world evidence.

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DIGITAL HEALTHCARE

Revibe Technologies Announces Clinical Development Updates for its Investigational FokusRx Prescription Digital Therapy for the Treatment of ADHD

Revibe technologies | February 09, 2022

Revibe technologies, a commercial-stage digital therapeutics company, announced today the positive results of their feasibility study examining the efficacy of FokusRx in school aged children with attention deficit hyperactivity disorder (ADHD). FokusRx is an investigational SaMD (Software as a Medical Device) that has the potential to provide a new nonpharmacologic approach to treating attention, focus and hyperactivity deficits associated with ADHD, and other mental health conditions. ADHD is one of the most commonly diagnosed and increasingly prevalent mental health disorders in children and adolescents.Inthe United States, 6.1 million children aged 2-17 years have been diagnosed with ADHD. Approximately 50% of families stop using prescription drug treatments for ADHD within a year.Over 30% of parents refuse pharmacologic treatment for their children with ADHD. In this, single-arm multi-rater feasibility study, parents (n= 38) and teachers (n= 26) rated youth aged 8-12 years with a parent-reported diagnosis of ADHD. Youth were attending in-person classroom learning and not taking medication for their ADHD. The study included a number of outcome measures including the ADHD-RS-5 (Home and School versions), Conners 4 – short version, Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P), and the Academic Performance Rating Scale (APRS). To be included in the analyses, youth had to have worn the Revibe Connect wearable device to school Monday to Friday for a at least three days per week or a minimum of 15 days total for a period of four weeks. "We are pleased that the feasibility study has proven to be a successful exercise that de-risks our upcoming randomized sham-controlled pivotal trial. The moderate to large effect sizes observed and change scores that exceed standards for minimally important (clinically significant) differences, provide encouraging preliminary evidence supporting the efficacy of our intervention", says Dr.Lindsay Ayearst, Chief Scientific Officer of Revibe. Revibe's Scientific and Medical Advisory Board member, Dr.Margaret Weiss, Director of Clinical Research in Child Psychiatry at Cambridge Health Alliance, stated, "These results are consistent across both symptoms and functioning, and across informants.They would translate into clinically significant change. Most impressive is the demonstration of an effect on academic performance." "The data from the classroom feasibility study suggests FokusRx can effectively and safely improve ADHD symptoms and functioning in school-aged children. It is our intention that FokusRx will provide kids and parents another option to help them succeed and reach their full potential. We are excited to begin designing our pivotal trial planned for the fall." Joseph Koziak, Chief Executive Officer of Revibe About FokusRx FokusRx is an investigational SaMD designed to provide a new nonpharmacologic approach to treating symptoms and impairment associated with ADHD. The FokusRx software is embedded within a dedicated smart watch to act as a digital therapeutic wearable. About Revibe Technologies Revibe Technologies is passionate about leveraging technology to help children and adults with focus and attention problems overcome obstacles in order to succeed in life. Revibe Technologies hopes to be a resource for students, parents, teachers, schools, and clinicians.

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AI

HealthRhythms and UCHealth partner to bring AI-based, Predictive Mental Health Platform to Millions of Patients

HealthRhythms | February 07, 2022

HealthRhythms, a digital mental health startup that seeks to become the behavioral health intelligence layer across all of healthcare, today announced a partnership with UCHealth to scale the benefits of its groundbreaking artificial intelligence (AI) -based digital platform to millions of patients. UCHealth is aColorado-based health care system that serves 2.3 million patients. The HealthRhythms' app uses smartphone sensors like an accelerometer to passively measure behavior relevant to mental health, and leverages AI to assess an individual's mental health status. It then uses that information to deliver personalized, timely interventions to improve mental health — sent directly to the patient's smartphone. This helps solve the universal problems of patient monitoring and early detection, enabling providers to effectively triage and treat patients across the risk continuum. "Partnering with UCHealth is a significant milestone in our commitment to transforming mental health care. HealthRhythms is the only company fully addressing this problem through valid measurement, high fidelity prediction and a highly personalized digital intervention platform that can be scaled to hundreds of millions of patients." HealthRhythms' CEOPaul Gilbert "The current health landscape is characterized by poor access to timely, high-quality mental health care. HealthRhythms' groundbreaking predictive analytics are unique and steeped in rigorous research," saidNeill Epperson, MD, chair of the University of Colorado Department of Psychiatry at theUniversity of Colorado Anschutz Medical Campus."Widespread utilization of HealthRhythms' technology will transform how we care for patients with mental health concerns." "Patients with complex medical conditions like heart disease commonly also have complex mental health challenges. It is impossible to appropriately treat these patients without addressing all of the issues contributing to their health," said Dr.Richard Zane, chief innovation officer at UCHealth and chair of emergency medicine at the University of Colorado School of Medicine. "The real breakthrough with HealthRhythms is that it allows all types of providers across all specialties to integrate behavioral health into their care without needing to be mental health experts." "Our vision is to have HealthRhythms on the phone of every patient who consents to it across the entire UCHealth system," saidKimberly A. Muller, executive director ofCU Innovations,a strategic healthcare fund affiliated with theUniversity of ColoradoAnschutz Medical Campus. "We recognize that mental health is, in fact, health. Addressing mental health is essential to everything we are looking to do for care integration. We believe HealthRhythms' data and insights will change the face of care." UCHealth, a nationally-recognized academic health system with 12 hospitals and hundreds of clinic locations is focused on improving access to behavioral health care throughoutColorado,WyomingandNebraska. By diagnosing behavioral health concerns at earlier stages, and by providing timely intervention, HealthRhythms improves all patients' lives, especially those with serious chronic diseases. HealthRhythms also announced the close of a highly oversubscribed$11 millionseed round led by GSR Ventures and investorBrook Byers, founding member ofKleiner Perkins Caufield& Byers. "This investor syndicate of 44 health tech leaders is one of the most accomplished, networked, and powerful I've ever seen," said Byers. "Securing this broad support behind HealthRhythms' world-class team for an important behavioral health mission is an awesome force multiplier." Dr.Sunny Kumar, a partner at GSR, will join the HealthRhythms Board of Directors. "Over the years, GSR has met with several hundred mental health companies, but HealthRhythms is one of the very few in which we have invested," said Dr. Kumar. "HealthRhythms is different because it addresses the core challenge in mental health care: improving both access and quality - the Holy Grail dimensions of mental healthcare - while enabling providers to deploy resources across a much broader population. The improvement in depression management that the company has demonstrated is a game changer, unmatched by virtually any available digital therapeutic that I'm aware of. The company's groundbreaking approach is rooted in a deep understanding of mental health and how to design digital experiences that are personally meaningful and easily woven into daily life." The HealthRhythms platform leverages over 40 years of laboratory and clinical research by HealthRhythms' co-founders who are regarded as pioneers and field leaders in the understanding of the causes and treatment of mental disorders. About HealthRhythms HealthRhythms is on a mission to become the behavioral health intelligence layer across all of healthcare and pharma. By capturing critical behavioral information — from social engagement to sleep/wake regulation to physical activity patterns — HealthRhythms provides a continuous, objective picture of individuals' behavioral health in their everyday environment, along with clinically-actionable insights about those behaviors. Pioneered by a team of successful startup founders and internationally-recognized leaders in tech, business, and medicine, HealthRhythms will redefine how mental health is understood and managed. About UCHealth UCHealth is an innovative, nonprofit health system that delivers the highest quality medical care with an excellent patient experience. UCHealthincludes 26,000 employees, 12 acute-care full-service hospitals and thousands of physicians acrossColorado, southernWyomingand westernNebraska. WithUniversity of Colorado Hospitalon the CU Ansxhutz Medical Campusas its academic anchor and the only adult academic medical center in the region, UCHealth is dedicated to providing unmatched patient care in the Rocky Mountain West. Offering more than 150 clinic locations, UCHealth pushes the boundaries of medicine, providing advanced treatments and clinical trials and improving health through innovation. About GSR Ventures GSR Ventures is an early-stage investor in technology companies developing AI-enabled healthcare technology, enterprise software, and consumer platforms.The Palo-Alto based GSR team includes founders, physicians and enterprise executives with unmatched industry expertise. Founded in 2004, the firm has more than$3 billionunder management. In addition to HealthRhythms, the U.S. portfolio includes Medable, Deep6 AI, Kinsa and AppliedVR.

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HEALTH TECHNOLOGY

Apollo Medical Holdings, Inc. Announces Acquisition of Value-Based Care Technology Platform Orma Health

Apollo Medical Holdings, Inc. | January 28, 2022

Apollo Medical Holdings, Inc. ("ApolloMed," and together with its subsidiaries and affiliated entities, the "Company"), a leading physician-centric, technology-powered healthcare company focused on enabling providers in the successful delivery of value-based care, today announced that it has acquired 100% of the fully diluted capitalization of Orma Health, Inc., and Provider Growth Solutions LLC (together, "Orma Health") in accordance with an agreement between ApolloMed, Orma Health and certain equity holders of Orma Health. Founded in 2020, Orma Health has helped many physician groups transition to and succeed in the delivery of value-based care, enabling them to focus on their passion—caring for patients. Orma Health's real-time Clinical AI platform ingests data from multiple sources and utilizes advanced risk-stratification models to identify patients for various clinical programs, including remote patient monitoring ("RPM"), mental health support, chronic disease management, and more. Its clinical platform is also deeply integrated with Orma Health's proprietary RPM ecosystem, which consists of smart health devices and a suite of technology tools to help manage patients' health. Through its suite of AI-driven solutions, Orma Health currently serves over 4,000 aligned Medicare beneficiaries in a Direct Contracting Entity ("DCE") and over 2,500 patients inCalifornia,Nevada,ArizonaandTexasthrough its RPM platform. "We are excited about integrating Orma Health's business and technological capabilities with those of ApolloMed, tapping their leadership team's experience in working with DCEs and helping risk-bearing provider groups in the delivery of value-based care as we augment our capabilities to support providers in various Centers for Medicare & Medicaid Services Innovation Models. We believe this acquisition will further differentiate ApolloMed's technology platform and analytic capabilities while adding complementary lines of business to our operations that serve as business development opportunities." Brandon Sim, Co-Chief Executive Officer of ApolloMed Through leveraging its proprietary technology platform and extensive value-based care experience, ApolloMed has historically demonstrated tremendous success participating in Centers for Medicare & Medicaid Services ("CMS") Innovation Models. The acquisition of Orma Health serves to accelerate ApolloMed's product roadmap in developing an end-to-end technology platform that enables providers to succeed in all CMS Innovation Models, including DCE. Orma Health's real-time Clinical AI and RPM technologies will also be integrated into ApolloMed's existing solutions for its managed care populations and will further enhance ApolloMed's technology and analytics offering to its 1.2 million Medicare Advantage, Managed Medicaid, Commercial, and ACA members nationwide. This will allow ApolloMed providers to receive an additional layer of real-time, actionable insights and continue delivering high-quality care to their patients, tailored to their membership populations. As ApolloMed looks to expand its membership and enter new geographies, there are significant business development opportunities in deepening Orma Health's relationships with existing RPM providers and patients and extending that to ApolloMed's managed care and CMS Innovation Model solutions and offerings. As part of the acquisition,Neil Ahuja, co-founder and Chief Executive Officer of Orma Health, will join ApolloMed as President, Provider Solutions and spearhead continued efforts to enable physicians to transition to value-based care models successfully.Yubin Park, co-founder and Chief Technology Officer of Orma Health, will join ApolloMed as Chief Analytics Officer and lead the continued development and integration of Orma Health's AI-driven provider enablement technology into ApolloMed's technology platform. Mr. Ahuja commented, "We are pleased to be joining ApolloMed, bringing Orma Health's core competencies in developing innovative healthcare technologies that drive tangible outcomes for providers and their patients. ApolloMed has been a leading healthcare management company with a long history of successfully and profitably empowering physicians in the delivery of value-based care, making it the perfect partner for us. We look forward to contributing our expertise to expanding ApolloMed's MSO capabilities and the potential future opportunities that lie ahead." Mr. Park added, "I am excited to begin working closely with the ApolloMed team on integrating Orma Health's technologies with that of ApolloMed. At Orma Health, we, like ApolloMed, believe that data is king. The information we gather and analyze about our members over the years is critical to our ability to deliver the best healthcare experience and outcomes for patients. We are thrilled that Orma Health is now a part of ApolloMed's worthy mission of empowering providers in delivering high-quality care and improved outcomes for its members." According to the terms of the agreement, a portion of the purchase price was paid in cash to the equity holders of Orma Health upon the closing of the transaction, another portion was paid in ApolloMed stock to the equity holders of Orma Health upon the closing of the transaction, and the remainder of the purchase price is to be paid in a combination of cash and stock to the equity holders contingent upon Orma Health achieving certain operational milestones over the 18 months after the closing. The Company will fund the transaction from cash on hand and shares of ApolloMed stock. About Apollo Medical Holdings, Inc. ApolloMed is a leading physician-centric, technology-powered, risk-bearing healthcare company. Leveraging its proprietary end-to-end technology solutions, ApolloMed operates an integrated healthcare delivery platform that enables providers to successfully participate in value-based care arrangements, thus empowering them to deliver high quality care to patients in a cost-effective manner. Headquartered inAlhambra, California, ApolloMed's subsidiaries and affiliates include management services organizations (MSOs), affiliated independent practice associations (IPAs), and a Next Generation Accountable Care Organization (NGACO).

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DIGITAL HEALTHCARE

Revibe Technologies Announces Clinical Development Updates for its Investigational FokusRx Prescription Digital Therapy for the Treatment of ADHD

Revibe technologies | February 09, 2022

Revibe technologies, a commercial-stage digital therapeutics company, announced today the positive results of their feasibility study examining the efficacy of FokusRx in school aged children with attention deficit hyperactivity disorder (ADHD). FokusRx is an investigational SaMD (Software as a Medical Device) that has the potential to provide a new nonpharmacologic approach to treating attention, focus and hyperactivity deficits associated with ADHD, and other mental health conditions. ADHD is one of the most commonly diagnosed and increasingly prevalent mental health disorders in children and adolescents.Inthe United States, 6.1 million children aged 2-17 years have been diagnosed with ADHD. Approximately 50% of families stop using prescription drug treatments for ADHD within a year.Over 30% of parents refuse pharmacologic treatment for their children with ADHD. In this, single-arm multi-rater feasibility study, parents (n= 38) and teachers (n= 26) rated youth aged 8-12 years with a parent-reported diagnosis of ADHD. Youth were attending in-person classroom learning and not taking medication for their ADHD. The study included a number of outcome measures including the ADHD-RS-5 (Home and School versions), Conners 4 – short version, Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P), and the Academic Performance Rating Scale (APRS). To be included in the analyses, youth had to have worn the Revibe Connect wearable device to school Monday to Friday for a at least three days per week or a minimum of 15 days total for a period of four weeks. "We are pleased that the feasibility study has proven to be a successful exercise that de-risks our upcoming randomized sham-controlled pivotal trial. The moderate to large effect sizes observed and change scores that exceed standards for minimally important (clinically significant) differences, provide encouraging preliminary evidence supporting the efficacy of our intervention", says Dr.Lindsay Ayearst, Chief Scientific Officer of Revibe. Revibe's Scientific and Medical Advisory Board member, Dr.Margaret Weiss, Director of Clinical Research in Child Psychiatry at Cambridge Health Alliance, stated, "These results are consistent across both symptoms and functioning, and across informants.They would translate into clinically significant change. Most impressive is the demonstration of an effect on academic performance." "The data from the classroom feasibility study suggests FokusRx can effectively and safely improve ADHD symptoms and functioning in school-aged children. It is our intention that FokusRx will provide kids and parents another option to help them succeed and reach their full potential. We are excited to begin designing our pivotal trial planned for the fall." Joseph Koziak, Chief Executive Officer of Revibe About FokusRx FokusRx is an investigational SaMD designed to provide a new nonpharmacologic approach to treating symptoms and impairment associated with ADHD. The FokusRx software is embedded within a dedicated smart watch to act as a digital therapeutic wearable. About Revibe Technologies Revibe Technologies is passionate about leveraging technology to help children and adults with focus and attention problems overcome obstacles in order to succeed in life. Revibe Technologies hopes to be a resource for students, parents, teachers, schools, and clinicians.

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AI

HealthRhythms and UCHealth partner to bring AI-based, Predictive Mental Health Platform to Millions of Patients

HealthRhythms | February 07, 2022

HealthRhythms, a digital mental health startup that seeks to become the behavioral health intelligence layer across all of healthcare, today announced a partnership with UCHealth to scale the benefits of its groundbreaking artificial intelligence (AI) -based digital platform to millions of patients. UCHealth is aColorado-based health care system that serves 2.3 million patients. The HealthRhythms' app uses smartphone sensors like an accelerometer to passively measure behavior relevant to mental health, and leverages AI to assess an individual's mental health status. It then uses that information to deliver personalized, timely interventions to improve mental health — sent directly to the patient's smartphone. This helps solve the universal problems of patient monitoring and early detection, enabling providers to effectively triage and treat patients across the risk continuum. "Partnering with UCHealth is a significant milestone in our commitment to transforming mental health care. HealthRhythms is the only company fully addressing this problem through valid measurement, high fidelity prediction and a highly personalized digital intervention platform that can be scaled to hundreds of millions of patients." HealthRhythms' CEOPaul Gilbert "The current health landscape is characterized by poor access to timely, high-quality mental health care. HealthRhythms' groundbreaking predictive analytics are unique and steeped in rigorous research," saidNeill Epperson, MD, chair of the University of Colorado Department of Psychiatry at theUniversity of Colorado Anschutz Medical Campus."Widespread utilization of HealthRhythms' technology will transform how we care for patients with mental health concerns." "Patients with complex medical conditions like heart disease commonly also have complex mental health challenges. It is impossible to appropriately treat these patients without addressing all of the issues contributing to their health," said Dr.Richard Zane, chief innovation officer at UCHealth and chair of emergency medicine at the University of Colorado School of Medicine. "The real breakthrough with HealthRhythms is that it allows all types of providers across all specialties to integrate behavioral health into their care without needing to be mental health experts." "Our vision is to have HealthRhythms on the phone of every patient who consents to it across the entire UCHealth system," saidKimberly A. Muller, executive director ofCU Innovations,a strategic healthcare fund affiliated with theUniversity of ColoradoAnschutz Medical Campus. "We recognize that mental health is, in fact, health. Addressing mental health is essential to everything we are looking to do for care integration. We believe HealthRhythms' data and insights will change the face of care." UCHealth, a nationally-recognized academic health system with 12 hospitals and hundreds of clinic locations is focused on improving access to behavioral health care throughoutColorado,WyomingandNebraska. By diagnosing behavioral health concerns at earlier stages, and by providing timely intervention, HealthRhythms improves all patients' lives, especially those with serious chronic diseases. HealthRhythms also announced the close of a highly oversubscribed$11 millionseed round led by GSR Ventures and investorBrook Byers, founding member ofKleiner Perkins Caufield& Byers. "This investor syndicate of 44 health tech leaders is one of the most accomplished, networked, and powerful I've ever seen," said Byers. "Securing this broad support behind HealthRhythms' world-class team for an important behavioral health mission is an awesome force multiplier." Dr.Sunny Kumar, a partner at GSR, will join the HealthRhythms Board of Directors. "Over the years, GSR has met with several hundred mental health companies, but HealthRhythms is one of the very few in which we have invested," said Dr. Kumar. "HealthRhythms is different because it addresses the core challenge in mental health care: improving both access and quality - the Holy Grail dimensions of mental healthcare - while enabling providers to deploy resources across a much broader population. The improvement in depression management that the company has demonstrated is a game changer, unmatched by virtually any available digital therapeutic that I'm aware of. The company's groundbreaking approach is rooted in a deep understanding of mental health and how to design digital experiences that are personally meaningful and easily woven into daily life." The HealthRhythms platform leverages over 40 years of laboratory and clinical research by HealthRhythms' co-founders who are regarded as pioneers and field leaders in the understanding of the causes and treatment of mental disorders. About HealthRhythms HealthRhythms is on a mission to become the behavioral health intelligence layer across all of healthcare and pharma. By capturing critical behavioral information — from social engagement to sleep/wake regulation to physical activity patterns — HealthRhythms provides a continuous, objective picture of individuals' behavioral health in their everyday environment, along with clinically-actionable insights about those behaviors. Pioneered by a team of successful startup founders and internationally-recognized leaders in tech, business, and medicine, HealthRhythms will redefine how mental health is understood and managed. About UCHealth UCHealth is an innovative, nonprofit health system that delivers the highest quality medical care with an excellent patient experience. UCHealthincludes 26,000 employees, 12 acute-care full-service hospitals and thousands of physicians acrossColorado, southernWyomingand westernNebraska. WithUniversity of Colorado Hospitalon the CU Ansxhutz Medical Campusas its academic anchor and the only adult academic medical center in the region, UCHealth is dedicated to providing unmatched patient care in the Rocky Mountain West. Offering more than 150 clinic locations, UCHealth pushes the boundaries of medicine, providing advanced treatments and clinical trials and improving health through innovation. About GSR Ventures GSR Ventures is an early-stage investor in technology companies developing AI-enabled healthcare technology, enterprise software, and consumer platforms.The Palo-Alto based GSR team includes founders, physicians and enterprise executives with unmatched industry expertise. Founded in 2004, the firm has more than$3 billionunder management. In addition to HealthRhythms, the U.S. portfolio includes Medable, Deep6 AI, Kinsa and AppliedVR.

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HEALTH TECHNOLOGY

Apollo Medical Holdings, Inc. Announces Acquisition of Value-Based Care Technology Platform Orma Health

Apollo Medical Holdings, Inc. | January 28, 2022

Apollo Medical Holdings, Inc. ("ApolloMed," and together with its subsidiaries and affiliated entities, the "Company"), a leading physician-centric, technology-powered healthcare company focused on enabling providers in the successful delivery of value-based care, today announced that it has acquired 100% of the fully diluted capitalization of Orma Health, Inc., and Provider Growth Solutions LLC (together, "Orma Health") in accordance with an agreement between ApolloMed, Orma Health and certain equity holders of Orma Health. Founded in 2020, Orma Health has helped many physician groups transition to and succeed in the delivery of value-based care, enabling them to focus on their passion—caring for patients. Orma Health's real-time Clinical AI platform ingests data from multiple sources and utilizes advanced risk-stratification models to identify patients for various clinical programs, including remote patient monitoring ("RPM"), mental health support, chronic disease management, and more. Its clinical platform is also deeply integrated with Orma Health's proprietary RPM ecosystem, which consists of smart health devices and a suite of technology tools to help manage patients' health. Through its suite of AI-driven solutions, Orma Health currently serves over 4,000 aligned Medicare beneficiaries in a Direct Contracting Entity ("DCE") and over 2,500 patients inCalifornia,Nevada,ArizonaandTexasthrough its RPM platform. "We are excited about integrating Orma Health's business and technological capabilities with those of ApolloMed, tapping their leadership team's experience in working with DCEs and helping risk-bearing provider groups in the delivery of value-based care as we augment our capabilities to support providers in various Centers for Medicare & Medicaid Services Innovation Models. We believe this acquisition will further differentiate ApolloMed's technology platform and analytic capabilities while adding complementary lines of business to our operations that serve as business development opportunities." Brandon Sim, Co-Chief Executive Officer of ApolloMed Through leveraging its proprietary technology platform and extensive value-based care experience, ApolloMed has historically demonstrated tremendous success participating in Centers for Medicare & Medicaid Services ("CMS") Innovation Models. The acquisition of Orma Health serves to accelerate ApolloMed's product roadmap in developing an end-to-end technology platform that enables providers to succeed in all CMS Innovation Models, including DCE. Orma Health's real-time Clinical AI and RPM technologies will also be integrated into ApolloMed's existing solutions for its managed care populations and will further enhance ApolloMed's technology and analytics offering to its 1.2 million Medicare Advantage, Managed Medicaid, Commercial, and ACA members nationwide. This will allow ApolloMed providers to receive an additional layer of real-time, actionable insights and continue delivering high-quality care to their patients, tailored to their membership populations. As ApolloMed looks to expand its membership and enter new geographies, there are significant business development opportunities in deepening Orma Health's relationships with existing RPM providers and patients and extending that to ApolloMed's managed care and CMS Innovation Model solutions and offerings. As part of the acquisition,Neil Ahuja, co-founder and Chief Executive Officer of Orma Health, will join ApolloMed as President, Provider Solutions and spearhead continued efforts to enable physicians to transition to value-based care models successfully.Yubin Park, co-founder and Chief Technology Officer of Orma Health, will join ApolloMed as Chief Analytics Officer and lead the continued development and integration of Orma Health's AI-driven provider enablement technology into ApolloMed's technology platform. Mr. Ahuja commented, "We are pleased to be joining ApolloMed, bringing Orma Health's core competencies in developing innovative healthcare technologies that drive tangible outcomes for providers and their patients. ApolloMed has been a leading healthcare management company with a long history of successfully and profitably empowering physicians in the delivery of value-based care, making it the perfect partner for us. We look forward to contributing our expertise to expanding ApolloMed's MSO capabilities and the potential future opportunities that lie ahead." Mr. Park added, "I am excited to begin working closely with the ApolloMed team on integrating Orma Health's technologies with that of ApolloMed. At Orma Health, we, like ApolloMed, believe that data is king. The information we gather and analyze about our members over the years is critical to our ability to deliver the best healthcare experience and outcomes for patients. We are thrilled that Orma Health is now a part of ApolloMed's worthy mission of empowering providers in delivering high-quality care and improved outcomes for its members." According to the terms of the agreement, a portion of the purchase price was paid in cash to the equity holders of Orma Health upon the closing of the transaction, another portion was paid in ApolloMed stock to the equity holders of Orma Health upon the closing of the transaction, and the remainder of the purchase price is to be paid in a combination of cash and stock to the equity holders contingent upon Orma Health achieving certain operational milestones over the 18 months after the closing. The Company will fund the transaction from cash on hand and shares of ApolloMed stock. About Apollo Medical Holdings, Inc. ApolloMed is a leading physician-centric, technology-powered, risk-bearing healthcare company. Leveraging its proprietary end-to-end technology solutions, ApolloMed operates an integrated healthcare delivery platform that enables providers to successfully participate in value-based care arrangements, thus empowering them to deliver high quality care to patients in a cost-effective manner. Headquartered inAlhambra, California, ApolloMed's subsidiaries and affiliates include management services organizations (MSOs), affiliated independent practice associations (IPAs), and a Next Generation Accountable Care Organization (NGACO).

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