New way to manipulate immune cells may treat cancer, autoimmune disease

CATHARINE PADDOCK | November 12, 2018

article image
Scientists have uncovered a new way to curb autoimmunity and stimulate the body to fight cancer. The method uses a previously unknown druggable pathway to manipulate immune cells. The discovery concerns a molecule called tetrahydrobiopterin (BH4), which is already well-known to those who study the biology of the brain and nervous system. However, new research reveals that BH4 has a previously unknown role — it helps to control the growth of T cells in the immune system.

Spotlight

St. Luke's Hospital

St. Luke’s Hospital is an independent, nonprofit healthcare provider committed to improving the quality of life for its patients and the community. Since its founding in 1866, St. Luke’s has grown from a single hospital location to an advanced network of care. It provides personalized healthcare services in over 60 specialty areas at its 493-bed hospital in Chesterfield, Mo. and offers 27 other locations across the greater St. Louis area, bringing quality healthcare services close to home.

OTHER ARTICLES

6 Tips On How To Not Let Your Anxieties Get The Best Of You

Article | October 26, 2020

Everybody deals with stress and anxiety however our anxieties can sometimes get the best of us. It’s important to know how to cope with your anxieties and fears if they get out of control. With this in mind, here are some tips that a person can use to help manage their daily stresses and anxieties. 1. Take a break: Sometimes, we get stressed out when everything happens all at once. When this happens, a person should take a deep breath and try to find something to do for a few minutes to get their mind off of the problem. A person could take a walk, listen to some music, read the newspaper, or do an activity that will give them a fresh perspective on things. 2. Carry a small notebook of positive statements with you: Whenever you come across an affirmation that makes you feel good, write it down in a small notebook and carry it around in your pocket. Whenever you feel anxious, open up your small notebook and read those statements. 3: You can’t predict the future: While the consequences of a particular fear may seem real, there are usually other factors that cannot be anticipated and can affect the results of any situation. We may be ninety-nine percent correct in predicting the future, but all it takes is for that one percent to make a world of difference. 4. Challenge your negative thinking with positive statements and realistic thinking: When encountering thoughts that make you fearful or depressed, challenge those thoughts by asking yourself questions that will maintain objectivity and common sense. Focus on the reality of your situation and not on your thoughts. 5. Divide your activities into separate steps: When facing a current or upcoming task that overwhelms you with a lot of anxiety, divide the task into a series of smaller steps and then complete each of the smaller tasks one step at a time. Completing these smaller activities will make the stress more manageable and increases your chances of success. 6. Take advantage of the help that is available around you: If possible, talk to a professional who can help you manage your depression and anxieties. They will be able to provide you with additional advice and insights on how to deal with your current problem. BIOGRAPHY Stan Popovich is the author of the popular managing fear book, “A Layman’s Guide To Managing Fear”. For more information about Stan’s book and to get some free mental health advice, please visit Stan’s website at http://www.managingfear.com

Read More

Trends, challenges and opportunities in UK’s healthcare sector in 2021

Article | October 26, 2020

COVID-19 has practically given a metaphorical high-voltage jolt to the whole world. It fell like a plague and affected humans in a way that nothing else has since the last global war. In short, it has reminded us of our mortality. As a result, improvement has become the new goal for the wise. According to Jana Abelovska, Head Pharmacist atClick Pharmacy, “COVID-19 has put the world on notice, especially the healthcare sector. Everything and everyone has seen its effects. But in this turmoil also come opportunities – an opportunity to grow and be better. It is a time of progress to help create a better and healthier tomorrow.”

Read More

Artificial intelligence and healthcare

Article | October 26, 2020

When we imagine the future, we think about "The Jetsons" or "Back to the Future." Although we are not flying our cars or transporting instantly to any location at the push of a button, Artificial Intelligence (AI) permeates our lives. Think about the last time Netflix picked out your last binge marathon, Gmail finished your sentence or Siri created your grocery list. These are all examples of AI. Companies use Al to predict actions customers will take based on their habits. Al is also shaping the healthcare industry. In fact, according to Becker's Healthcare, Al will save healthcare $52 billion by 2021. Al bots track consumer health, enabling doctors to more easily access patients' health information. Apps and chat bots bridge the communication between the patient and the healthcare provider. Patients receive advice from their bedside and save time by using Al. Al takes a patient's health information and creates recommendations that can prevent further illnesses from occurring. A recent article provides insights on Al and data as a "what is next" for the communication industry.

Read More

A snapshot of the precision medicine landscape

Article | October 26, 2020

The global market for precision medicine is projected to top more than $84.5 billion by 2024. Targeted therapies for rare, genetic diseases, cancer and chronic conditions come with the hope of a cure. Companies such as Roche, Novartis, Spark Therapeutics, Pfizer, Editas and BioMarin are among the pharma players in this space. There seem to be new developments in precision medicine on almost a weekly basis. So what do educational institutions need to do to create fertile ground for gene therapy research to produce the next generation of companies developing these therapies? And what needs to happen to facilitate data sharing, ensure access to genome sequencing and these promising therapies?

Read More

Spotlight

St. Luke's Hospital

St. Luke’s Hospital is an independent, nonprofit healthcare provider committed to improving the quality of life for its patients and the community. Since its founding in 1866, St. Luke’s has grown from a single hospital location to an advanced network of care. It provides personalized healthcare services in over 60 specialty areas at its 493-bed hospital in Chesterfield, Mo. and offers 27 other locations across the greater St. Louis area, bringing quality healthcare services close to home.

Events